Anticorps Recombinant de lapin anti-HLA-DMA

HLA-DMA Recombinant Antibody for Cytometric bead array, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

230155D3

N° de cat : 82899-1-PBS

Synonymes

230155D3, D6S222E, DMA, DMA protein, DMA protein MHC class II antigen Major histocompatibility complex, class II, DM alpha cDNA FLJ75740, highly similar to Homo sapiens major histocompatibility complex, class II, DM alpha

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Galerie de données de validation

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  Cytometric bead array standard curve of MP00018-1

  Cytometric bead array standard curve of MP00018-1, HLA-DMA Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 82899-5-PBS. Detection antibody: 82899-1-PBS. Standard: Ag2452. Range: 0.625-20 ng/mL.

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  Cytometric bead array standard curve of MP00018-3

  Cytometric bead array standard curve of MP00018-3, HLA-DMA Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 82899-3-PBS. Detection antibody: 82899-1-PBS. Standard: Ag2452. Range: 0.625-20 ng/mL.

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  Affinity and Kinetic Characterization of 82899-1-RR

  Biolayer interferometry (BLl) kinetic assays of 82899-1-RR against Human HLA-DMA were performed. The affinity constant is below 1 pM.

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Informations sur le produit

82899-1-PBS cible HLA-DMA dans les applications de Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: HLA-DMA Protéine recombinante Ag2452
• Nom complet: major histocompatibility complex, class II, DM alpha
• Masse moléculaire calculée: 261 aa, 29 kDa
• Numéro d’acquisition GenBank: BC026279
• Symbole du gène: HLA-DMA
• Identification du gène (NCBI): 3108
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Human major histocompatibility complex (MHC) antigens, also referred to as human leukocyte antigens (HLA), are encoded by genes located on the short arm of chromosome 6 (6p21.3). There are two classes of HLA antigens: class I (HLA-A, B and C) and class II (HLA-D). The class II molecules are composed of two non-covalently associated alpha and beta chains. HLA-DMA and HLA-DMB form a functional heterodimer that is critical in the pathway of class II antigen presentation. HLA-DM plays a critical role in catalyzing the release of Class II HLA-associated invariant chain-derived peptides (CLIP) from newly synthesized class II HLA molecules and freeing the peptide binding site for acquisition of antigenic peptides.

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