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Anticorps Polyclonal de lapin anti-HMGB4

HMGB4 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 12787-1-PBS

Synonymes

Galerie de données de validation

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  • Western Blot (WB) analysis of mouse testis tissue using HMGB4 Polyclonal antibody (12787-1-AP)

    WB analysis of mouse testis using 12787-1-AP (same clone as 12787-1-PBS)

    mouse testis tissue were subjected to SDS PAGE followed by western blot with 12787-1-AP (HMGB4 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12787-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of human testis tissue using HMGB4 Polyclonal antibody (12787-1-AP)

    WB analysis of human testis using 12787-1-AP (same clone as 12787-1-PBS)

    human testis tissue were subjected to SDS PAGE followed by western blot with 12787-1-AP (HMGB4 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12787-1-PBS in a different storage buffer formulation.

Informations sur le produit

12787-1-PBS cible HMGB4 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

Réactivité Humain, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène HMGB4 Protéine recombinante Ag3503
Nom complet high-mobility group box 4
Masse moléculaire calculée 186 aa, 22 kDa
Poids moléculaire observé 22-25 kDa
Numéro d’acquisition GenBankBC021180
Symbole du gène HMGB4
Identification du gène (NCBI) 127540
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

High mobility group protein B4 (HMGB4) is a new member in the family of HMGB proteins. Unlike other HMGB-proteins, it is a mammalian specific protein that has two HMGB-boxes but lacks the acidic tail. HMGB4 is strongly and preferentially expressed in the adult mouse testis and weakly in the brain, but not in many other tissues (PMID: 18987332). It binds strongly to nuclear structures, regulates chromatin and mediates differentiation of neuronal cells (PMID: 27608812).

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