Anticorps Polyclonal de lapin anti-HMGCR

• Phare
• Validé par KD/KO

HMGCR Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 13533-1-PBS

Synonymes

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Galerie de données de validation

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  IHC staining of human liver cancer using 13533-1-AP (same clone as 13533-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 13533-1-AP (HMGCR antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13533-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 13533-1-AP (same clone as 13533-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 13533-1-AP (HMGCR antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13533-1-PBS in a different storage buffer formulation.

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  IHC staining of human heart using 13533-1-AP (same clone as 13533-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 13533-1-AP (HMGCR Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 13533-1-PBS in a different storage buffer formulation.

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  IHC staining of human heart using 13533-1-AP (same clone as 13533-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 13533-1-AP (HMGCR Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 13533-1-PBS in a different storage buffer formulation.

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  IHC staining of human small intestine using 13533-1-AP (same clone as 13533-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 13533-1-AP (HMGCR antibody) at dilution of 1:1000 (under 10x lens).. This data was developed using the same antibody clone with 13533-1-PBS in a different storage buffer formulation.

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  IHC staining of human small intestine using 13533-1-AP (same clone as 13533-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 13533-1-AP (HMGCR antibody) at dilution of 1:1000 (under 40x lens).. This data was developed using the same antibody clone with 13533-1-PBS in a different storage buffer formulation.

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Informations sur le produit

13533-1-PBS cible HMGCR dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: HMGCR Protéine recombinante Ag4444
• Nom complet: 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
• Masse moléculaire calculée: 888 aa, 95 kDa
• Numéro d’acquisition GenBank: BC033692
• Symbole du gène: HMGCR
• Identification du gène (NCBI): 3156
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

HMGCR(3-hydroxy-3-methylglutaryl-coenzyme A reductase) is also named as HMG-CoA reductase and belongs to the HMG-CoA reductase family. This protein exists as a 97-kDa glycoprotein in the endoplasmic reticulum (ER) and is the rate-determining enzyme of the biosynthesis pathway(PMID:15830340).The ectopic expression of either full-length HMGCR or its novel splice variant promotes dysregulation of the MVA pathway. And the ectopic expression of cHMGCR-FL(60 kDa) and cHMGCR-D13(55 kDa) can be detected in HepG2 cells(PMID:20696928).This protein is also can exsit as a oligomer(PMID:20696928).

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