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Anticorps Monoclonal anti-HMMR

HMMR Monoclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1C6B5

N° de cat : 68718-1-PBS

Synonymes

RHAMM, Receptor for hyaluronan-mediated motility, Intracellular hyaluronic acid-binding protein, IHABP, CD168

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using HMMR Monoclonal antibody (68718-1-Ig)

    WB analysis using 68718-1-Ig (same clone as 68718-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68718-1-Ig (HMMR antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68718-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HepG2 cells using HMMR Monoclonal antibody (68718-1-Ig)

    IF Staining of HepG2 using 68718-1-Ig (same clone as 68718-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using HMMR antibody (68718-1-Ig, Clone: 1C6B5 ) at dilution of 1:800 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Mouse Recombinant Secondary Antibody (H+L) (RGAM002). This data was developed using the same antibody clone with 68718-1-PBS in a different storage buffer formulation.

Informations sur le produit

68718-1-PBS cible HMMR dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Mouse / IgG1
Clonalité Monoclonal
Type Anticorps
Immunogène HMMR Protéine recombinante Ag33723
Nom complet hyaluronan-mediated motility receptor (RHAMM)
Masse moléculaire calculée84 kDa
Poids moléculaire observé 84 kDa
Numéro d’acquisition GenBankNM_012484
Symbole du gène HMMR
Identification du gène (NCBI) 3161
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine G
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Hyaluronan-mediated motility receptor (HMMR), also termed CD168, was first described by Turley in murine cells . It is reported that HMMR has an extensive coiled-coil structure (CC) that contains multiple sites for interactive partners. Initially, HMMR was considered a novel hyaluronan-mediated motility receptor and a microtubule-associated spindle assembly factor. Full-length human RHAMM is an 85  kDa coiled-coil protein that occurs both in intracellular and extracellular compartments. It has highly restricted and tightly regulated expression in most normal tissues, but is one of a number of oncogenic proteins that are exported to the cell surface in response to tissue stress by unconventional transport mechanisms. (PMID: 36750558, PMID: 30249497)

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