Anticorps Recombinant de lapin anti-HMMR-Specific

HMMR-Specific Recombinant Antibody for IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242332G4

N° de cat : 85094-1-PBS

Synonymes

HMMR, 242332G4, CD168, IHABP, Intracellular hyaluronic acid-binding protein

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Galerie de données de validation

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  IHC staining of human tonsillitis using 85094-1-RR (same clone as 85094-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 85094-1-RR (HMMR-Specific antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85094-1-PBS in a different storage buffer formulation.

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  IHC staining of human tonsillitis using 85094-1-RR (same clone as 85094-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 85094-1-RR (HMMR-Specific antibody) at dilution of 1:500 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85094-1-PBS in a different storage buffer formulation.

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  IF Staining of HepG2 using 85094-1-RR (same clone as 85094-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using HMMR-Specific antibody (85094-1-RR, Clone: 242332G4 ) at dilution of 1:1000 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 85094-1-PBS in a different storage buffer formulation.

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Informations sur le produit

85094-1-PBS cible HMMR-Specific dans les applications de IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: hyaluronan-mediated motility receptor (RHAMM)
• Masse moléculaire calculée: 84 kDa
• Numéro d’acquisition GenBank: NM_001142556
• Symbole du gène: HMMR
• Identification du gène (NCBI): 3161
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Hyaluronan-mediated motility receptor (HMMR), also termed CD168, was first described by Turley in murine cells . It is reported that HMMR has an extensive coiled-coil structure (CC) that contains multiple sites for interactive partners. Initially, HMMR was considered a novel hyaluronan-mediated motility receptor and a microtubule-associated spindle assembly factor. Full-length human RHAMM is an 85  kDa coiled-coil protein that occurs both in intracellular and extracellular compartments. It has highly restricted and tightly regulated expression in most normal tissues, but is one of a number of oncogenic proteins that are exported to the cell surface in response to tissue stress by unconventional transport mechanisms. (PMID: 36750558, PMID: 30249497)

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