Anticorps Polyclonal de lapin anti-HOGA1

HOGA1 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 27755-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 27755-1-AP (same clone as 27755-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 27755-1-AP (HOGA1 antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27755-1-PBS in a different storage buffer formulation.

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Informations sur le produit

27755-1-PBS cible HOGA1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: HOGA1 Protéine recombinante Ag26849
• Nom complet: chromosome 10 open reading frame 65
• Poids moléculaire observé: 35 kDa
• Numéro d’acquisition GenBank: BC045550
• Symbole du gène: HOGA1
• Identification du gène (NCBI): 112817
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

HOGA1 (4-hydroxy-2-oxoglutarate aldolase), also known as C10orf65, DHDPSL, is a mitochondrial enzyme that plays a gatekeeper role in hydroxyproline metabolis. HOGA1 is primarily expressed in liver and kidney and catalyzes the final step of mitochondrial hydroxyproline metabolism\ from 4-hydroxy-2-oxoglutarate to glyoxylate and pyruvate (PMID: 31696211). Identification of mutations in the HOGA1 gene as the cause of autosomal recessive primary hyperoxaluria (PH) type III has revitalized research in the field of PH and related stone disease (PMID: 22781098).

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