Anticorps Polyclonal de lapin anti-HOXB9

HOXB9 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 18894-1-PBS

Synonymes

HOX2E, HOX2.5, Homeobox protein Hox-B9, Homeobox protein Hox-2E, Homeobox protein Hox-2.5

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Galerie de données de validation

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  WB analysis using 18894-1-AP (same clone as 18894-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 18894-1-AP (HOXB9 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18894-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 18894-1-AP (same clone as 18894-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 18894-1-AP (HOXB9 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18894-1-PBS in a different storage buffer formulation.

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Informations sur le produit

18894-1-PBS cible HOXB9 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: HOXB9 Protéine recombinante Ag13502
• Nom complet: homeobox B9
• Masse moléculaire calculée: 250 aa, 28 kDa
• Poids moléculaire observé: 30-32 kDa
• Numéro d’acquisition GenBank: BC015565
• Symbole du gène: HOXB9
• Identification du gène (NCBI): 3219
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

HOXB9 is a member of the Homeobox (HOX) gene family, which plays a crucial role in embryonic development and is involved in the regulation of gene expression during this process. In addition to its role in embryogenesis, HOXB9 has been implicated in various cancers, including breast and prostate cancer. It is overexpressed in breast cancer tissue and is regulated by estrogen, playing a critical role in angiogenesis. HOXB9 overexpression has been shown to stimulate three-dimensional colony formation in soft-agar assays, indicating its role in tumorigenesis. Furthermore, HOXB9 binds to the promoters of various tumor growth and angiogenic factors, regulating their expression, and its homeodomain plays a crucial role in transcriptional regulation and tumorigenesis.

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