Anticorps Polyclonal de lapin anti-HOXC13

HOXC13 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 27002-1-PBS

Synonymes

HOX3G

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Galerie de données de validation

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  WB analysis using 27002-1-AP (same clone as 27002-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 27002-1-AP (HOXC13 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27002-1-PBS in a different storage buffer formulation.

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  IF Staining of HeLa using 27002-1-AP (same clone as 27002-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed HeLa cells using HOXC13 antibody (27002-1-AP) at dilution of 1:400 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). This data was developed using the same antibody clone with 27002-1-PBS in a different storage buffer formulation.

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Informations sur le produit

27002-1-PBS cible HOXC13 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: HOXC13 Protéine recombinante Ag25544
• Nom complet: homeobox C13
• Masse moléculaire calculée: 35 kDa, 330 aa
• Poids moléculaire observé: 38 kDa
• Numéro d’acquisition GenBank: BC090850
• Symbole du gène: HOXC13
• Identification du gène (NCBI): 3229
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

HOXC13 is a member of HOX proteins. The HOX family includes 39 paralogous proteins expressed from the HOXA, HOXB, HOXC, and HOXD gene clusters, and these function early in embryonic development to establish cell and tissue identity and to regulate cell proliferation, differentiation, and survival (PMID: 30974835). Human HOXC13, which is expressed in the hair follicle and nail matrix, is involved in the regulation of keratin gene expression (PMID: 11714694). Mutations in human HOXC13 cause ectodermal dysplasia 9, a severe defect of hair and nails (PMID: 23063621).

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