Anticorps Polyclonal de lapin anti-HOXC4

• Phare
• Validé par KD/KO

HOXC4 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 14321-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 14321-1-AP (same clone as 14321-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 14321-1-AP (HOXC4 antibody) at dilution of 1:15000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14321-1-PBS in a different storage buffer formulation.

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  WB analysis of Jurkat using 14321-1-AP (same clone as 14321-1-PBS)

  WB result of HOXC4 antibody (14321-1-AP; 1:6000; incubated at room temperature for 1.5 hours) with sh-Control and sh-HOXC4 transfected Jurkat cells. This data was developed using the same antibody clone with 14321-1-PBS in a different storage buffer formulation.

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Informations sur le produit

14321-1-PBS cible HOXC4 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat

• Réactivité: Humain, rat
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: HOXC4 Protéine recombinante Ag5563
• Nom complet: homeobox C4
• Masse moléculaire calculée: 30 kDa
• Poids moléculaire observé: 39 kDa
• Numéro d’acquisition GenBank: BC050442
• Symbole du gène: HOXC4
• Identification du gène (NCBI): 3221
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The class I homeobox (HOX) family of homeodomain-containing transcription factors has 39 members in mammals. These genes are distributed throughout the genome in four clusters: HOXA (7p15), HOXB (17q21), HOXC (12q13), and HOXD (2q31). HOX genes are known to act as transcription factors, playing an essential regulatory role in the temporal and spatial development of the embryo. HOXC family members are not expressed in normal prostate tissue but increased expression of HOXC genes is commonly detected in prostate cancers. HOXC4 is expressed in GC B cells and HoxC4 expression is specifically up-regulated by the same stimuli that induce AID expression (LPS, CD154 and IL-4). The calculated molecular weight of HOXC4 is 30 kDa. Sometimes higher molecular weight around 39 kDa can also be observed, which may be a modified variant of HOXC4 (PMID: 23178148, 32012197, 35400027).

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