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Anticorps Polyclonal de lapin anti-HOXD3

HOXD3 Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 10496-1-PBS

Synonymes

Galerie de données de validation

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  • Immunohistochemistry (IHC) staining of mouse testis tissue using HOXD3 Polyclonal antibody (10496-1-AP)

    IHC staining of mouse testis using 10496-1-AP (same clone as 10496-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 10496-1-AP (HOXD3 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10496-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of U2OS cells using HOXD3 Polyclonal antibody (10496-1-AP)

    IF Staining of U2OS using 10496-1-AP (same clone as 10496-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed U2OS cells using HOXD3 antibody (10496-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-Phalloidin (red). This data was developed using the same antibody clone with 10496-1-PBS in a different storage buffer formulation.

Informations sur le produit

10496-1-PBS cible HOXD3 dans les applications de IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

Réactivité Humain, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène HOXD3 Protéine recombinante Ag0768
Nom complet homeobox D3
Masse moléculaire calculée 46 kDa
Numéro d’acquisition GenBankBC005124
Symbole du gène HOXD3
Identification du gène (NCBI) 3232
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Homeobox D3 (HOXD3), a member of the Homeobox (Hox) family of master transcription factors, is a homeobox transcription factor that promotes angiogenesis and collagen synthesis. HOXD3 is expressed during normal embryogenesis, skin development, and fetal wound healing (PMID: 14633614). The overexpression of HOXD3 plays a critical role in breast cancer stemness and drug resistance via integrin β3-mediated Wnt/β-catenin signaling (PMID: 29698974).

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