Anticorps Monoclonal anti-HSPB11

• Phare
• Validé par KD/KO

HSPB11 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2D11B3

N° de cat : 68059-1-PBS

Synonymes

Heat shock protein beta-11, Heat shock protein beta 11, FAP232, CFAP232, C1orf41

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Galerie de données de validation

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  WB analysis using 68059-1-Ig (same clone as 68059-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68059-1-Ig (HSPB11 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68059-1-PBS in a different storage buffer formulation.

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  WB analysis of HeLa using 68059-1-Ig (same clone as 68059-1-PBS)

  WB result of HSPB11 antibody (68059-1-Ig; 1:3000; incubated at room temperature for 1.5 hours) with sh-Control and sh-HSPB11 transfected HeLa cells. This data was developed using the same antibody clone with 68059-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68059-1-PBS cible HSPB11 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: HSPB11 Protéine recombinante Ag8804
• Nom complet: heat shock protein family B (small), member 11
• Masse moléculaire calculée: 144 aa, 16 kDa
• Poids moléculaire observé: 20 kDa
• Numéro d’acquisition GenBank: BC005245
• Symbole du gène: HSPB11
• Identification du gène (NCBI): 51668
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

HSPB11 (Heat shock protein beta-11), also known as IFT25, was originally identified as a small heat shock protein. Recently it has been identified as a component of IFT complex B. It has been demonstrated that IFT25 is not required for ciliary assembly but is required for proper Hedgehog signaling, which in mammals occurs within cilia. Cilia lacking IFT25 have defects in the signal-dependent transport of multiple Hedgehog components and fail to activate the pathway upon stimulation.

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