Anticorps Polyclonal de lapin anti-HTR1B

HTR1B Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, ELISA

Conjugaison

Non conjugué

Publications(3)

N° de cat : 22189-1-AP

Synonymes

5 HT 1B, 5 HT 1D beta, 5 HT1B, 5 HT1DB, HTR1B, HTR1D2, HTR1DB, S12, Serotonin 1D beta receptor, Serotonin receptor 1B

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Galerie de données de validation

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  WB analysis of human placenta using 22189-1-AP

  human placenta tissue were subjected to SDS PAGE followed by western blot with 22189-1-AP (HTR1B antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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  WB analysis of mouse placenta using 22189-1-AP

  mouse placenta tissue were subjected to SDS PAGE followed by western blot with 22189-1-AP (HTR1B antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: tissu placentaire humain, tissu placentaire de souris

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• WB: See 2 publications below
• IHC: See 2 publications below

Informations sur le produit

22189-1-AP cible HTR1B dans les applications de WB, IHC, ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Réactivité citée: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: HTR1B Protéine recombinante Ag16753
• Nom complet: 5-hydroxytryptamine (serotonin) receptor 1B
• Masse moléculaire calculée: 390 aa, 44 kDa
• Poids moléculaire observé: 40-44 kDa
• Numéro d’acquisition GenBank: BC096207
• Symbole du gène: HTR1B
• Identification du gène (NCBI): 3351
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

HTR1B, also known as 5-HT1B, 5-HT1DB, HTR1D2, HTR1DB, and S12, belongs to the G-protein coupled receptor 1 family. HTR1B is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of HTR1B is mediated by G proteins that inhibit adenylate cyclase activity.

Publications

Species	Application	Title
mouse	WB	Ecotoxicol Environ Saf; Heat stress affects fetal brain and intestinal function associated with the alterations of placental barrier in late pregnant mouse.; Authors - Huiduo Guo
human	WB,IHC	Heliyon; HTR1B regulates mitochondrial homeostasis and mitophagy by activating the ERK/ MAPK signalling pathway during human embryonic arrest; Authors - Si-Min Ding
mouse	IHC	Eur J Neurosci; The alteration of serotonergic markers in the amygdala and raphe nuclei of oestrogen receptor β knock-out female mice; Authors - Daniel Kalinowski

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