Anticorps Polyclonal de lapin anti-HTR7

HTR7 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 13830-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of mouse brain using 13830-1-AP (same clone as 13830-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 13830-1-AP (HTR7 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13830-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse spleen using 13830-1-AP (same clone as 13830-1-PBS)

  mouse spleen tissue were subjected to SDS PAGE followed by western blot with 13830-1-AP (HTR7 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13830-1-PBS in a different storage buffer formulation.

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  IHC staining of human brain using 13830-1-AP (same clone as 13830-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 13830-1-AP (HTR7 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 13830-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human brain using 13830-1-AP (same clone as 13830-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 13830-1-AP (HTR7 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 13830-1-PBS in a different storage buffer formulation.

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Informations sur le produit

13830-1-PBS cible HTR7 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: HTR7 Protéine recombinante Ag4742
• Nom complet: 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)
• Masse moléculaire calculée: 445 aa, 49 kDa
• Poids moléculaire observé: 50-55 kDa
• Numéro d’acquisition GenBank: BC047526
• Symbole du gène: HTR7
• Identification du gène (NCBI): 3363
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Serotonin (5-hydroxytryptamine; 5-HT) acts as a neurotransmitter and neuromodulator in the central nervous system(CNS) (PMID:23100172). The behavioral effects of 5-HT are mediated by a large family of specific 5-HT receptors. HTR7 (5-hydroxytryptamine receptor 7) is a G protein-coupled receptor (GPCR), and many transcription factors can bind to its promoter, such as AP2, EGR-1, and MAZ (PMID:34164474). It is located in different brain regions, such as the hypothalamus, thalamus, cerebral cortex, and hippocampus (PMID:29637287). HTR7 is associated with circadian rhythm, anxiety, depression, schizophrenia, nociception, and memory (PMID:9154233).

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