Anticorps Polyclonal de lapin anti-HTRA3

HTRA3 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31369-1-PBS

Synonymes

Tasp, PRSP

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Galerie de données de validation

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  WB analysis using 31369-1-AP (same clone as 31369-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31369-1-AP (HTRA3 antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31369-1-PBS in a different storage buffer formulation.

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Informations sur le produit

31369-1-PBS cible HTRA3 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: HTRA3 Protéine recombinante Ag35448
• Nom complet: HtrA serine peptidase 3
• Masse moléculaire calculée: 49kDa，453aa
• Poids moléculaire observé: 49 kDa
• Numéro d’acquisition GenBank: NM_053044.4
• Symbole du gène: HTRA3
• Identification du gène (NCBI): 94031
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

HTRA3 is one of the four members of the HtrA family proteins, with a secreted multidomain and serine protease activity, which plays an important role in cellular stress response, protein homeostasis, and apoptosis. HTRA3 is highly expressed in the decidual cells in the late secretory phase of the menstrual cycle and throughout pregnancy, and in most trophoblast cell types, apart from the invading interstitial trophoblast during the first trimester. HTRA3 and its family members are down-regulated in several cancers and are proposed as tumor suppressors (PMID: 21321049, 22229724).

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