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Anticorps Recombinant de lapin anti-HVEM/TNFRSF14

HVEM/TNFRSF14 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

250728B12

N° de cat : 81078-6-PBS

Synonymes

TNFRSF14, ATAR, CD270, Herpes virus entry mediator A, Herpesvirus entry mediator A

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of human urine sample using HVEM/TNFRSF14 Recombinant antibody (81078-6-RR)

    WB analysis of human urine using 81078-6-RR (same clone as 81078-6-PBS)

    human urine sample was subjected to SDS PAGE followed by western blot with 81078-6-RR (HVEM/TNFRSF14 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 81078-6-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 81078-6-RR

    Affinity and Kinetic Characterization of 81078-6-RR

    Biolayer interferometry (BLl) kinetic assays of 81078-6-RR against Human HVEM/TNFRSF14 were performed. The affinity constant is 3.00 nM.

Informations sur le produit

81078-6-PBS cible HVEM/TNFRSF14 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène HVEM/TNFRSF14 Protéine recombinante Eg1275
Nom complet tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
Masse moléculaire calculée 30 kDa
Poids moléculaire observé40 kDa
Numéro d’acquisition GenBankBC002794
Symbole du gène TNFRSF14
Identification du gène (NCBI) 8764
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine A
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The mammalian tumor necrosis factor receptor (TNFR) family consists of 10 cell-surface proteins that regulate development and homeostasis of the immune system. Member 14 of TNFR (TNFRSF14, also named as TR2, ATAR, HVEA, HVEM, LIGHTR) was also identified as a mediator of herpesvirus entry into mammalian cells. The cytoplasmic region of TNFRSF14 bound to several members of the TNFR-associated factor (TRAF) family, namely TRAF1, TRAF2, TRAF3, and TRAF5. Transient transfection into human 293 cells caused marked activation of nuclear factor- B (NF- B), a transcriptional regulator of multiple immunomodulatory and inflammatory genes.

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