Anticorps Recombinant de lapin anti-HVEM/TNFRSF14

HVEM/TNFRSF14 Recombinant Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

CloneNo.

250728B12

N° de cat : 81078-6-RR

Synonymes

TNFRSF14, ATAR, CD270, Herpes virus entry mediator A, Herpesvirus entry mediator A

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Galerie de données de validation

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  WB analysis of human urine using 81078-6-RR

  human urine sample was subjected to SDS PAGE followed by western blot with 81078-6-RR (HVEM/TNFRSF14 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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  Affinity and Kinetic Characterization of 81078-6-RR

  Biolayer interferometry (BLl) kinetic assays of 81078-6-RR against Human HVEM/TNFRSF14 were performed. The affinity constant is 3.00 nM.

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Applications testées

• Résultats positifs en WB: urine humaine

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

81078-6-RR cible HVEM/TNFRSF14 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: HVEM/TNFRSF14 Protéine recombinante Eg1275
• Nom complet: tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
• Masse moléculaire calculée: 30 kDa
• Poids moléculaire observé: 40 kDa
• Numéro d’acquisition GenBank: BC002794
• Symbole du gène: TNFRSF14
• Identification du gène (NCBI): 8764
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

The mammalian tumor necrosis factor receptor (TNFR) family consists of 10 cell-surface proteins that regulate development and homeostasis of the immune system. Member 14 of TNFR (TNFRSF14, also named as TR2, ATAR, HVEA, HVEM, LIGHTR) was also identified as a mediator of herpesvirus entry into mammalian cells. The cytoplasmic region of TNFRSF14 bound to several members of the TNFR-associated factor (TRAF) family, namely TRAF1, TRAF2, TRAF3, and TRAF5. Transient transfection into human 293 cells caused marked activation of nuclear factor- B (NF- B), a transcriptional regulator of multiple immunomodulatory and inflammatory genes.

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