Anticorps Recombinant de lapin anti-ICAM5

ICAM5 Recombinant Antibody for WB, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

rat, souris

Applications

WB, IP, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

243100H5

N° de cat : 85941-1-PBS

Synonymes

Icam3, ICAM-5, Intercellular adhesion molecule 5, Telencephalin, Tlcn

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Galerie de données de validation

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  WB analysis using 85941-1-RR (same clone as 85941-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85941-1-RR (Icam5 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85941-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse brain using 85941-1-RR (same clone as 85941-1-PBS)

  IP result of anti-ICAM5 (IP:85941-1-RR, 4ug; Detection:85941-1-RR 1:4000) with mouse brain tissue lysate 2120 ug. This data was developed using the same antibody clone with 85941-1-PBS in a different storage buffer formulation.

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Informations sur le produit

85941-1-PBS cible ICAM5 dans les applications de WB, IP, Indirect ELISA et montre une réactivité avec des échantillons rat, souris

• Réactivité: rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: ICAM5 Protéine recombinante Eg2868
• Nom complet: intercellular adhesion molecule 5, telencephalin
• Masse moléculaire calculée: 97 kDa
• Poids moléculaire observé: 150 kDa
• Numéro d’acquisition GenBank: N/A
• Symbole du gène: Icam5
• Identification du gène (NCBI): 15898
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ICAM-5, also known as telencephalin, is a type I integral membrane glycoprotein of the immunoglobulin superfamily. It is specifically expressed in the postnatal excitatory neuronal cell bodies, dendritic shafts, and dendritic filopodia of the telencephalon. ICAM-5 functions in both the immune and nervous systems. ICAM-5 strongly stimulates neurite outgrowth. It is cleaved by matrix metalloproteases upon activation of glutamate receptors or degraded through endocytosis resulting in increased spine maturation. The cleaved soluble fragment of ICAM-5 is immunosuppressive, which may be important in neuronal inflammatory diseases. (PMID: 10402269; 17682049; 25300135)

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