Anticorps Recombinant de lapin anti-ICOS/CD278

ICOS/CD278 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

241770G11

N° de cat : 98214-1-RR

Synonymes

ICOS, CVID1, CD278, AILIM, Activation-inducible lymphocyte immunomediatory molecule

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Galerie de données de validation

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  FC experiment of human PBMCs using 98214-1-RR

  1x10^6 untreated or PHA treated human PBMCs were surface stained with 0.25 ug Anti-Human ICOS/CD278 Rabbit Recombinant Antibody (98214-1-RR, Clone: 241770G11) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with APC Anti-Human CD3 (OKT3) Mouse IgG2a Recombinant Antibody (APC-65569, Clone: OKT3). Cells were not fixed.

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  FC experiment of human PBMCs using 98214-1-RR

  1x10^6 PHA treated human PBMCs were surface stained with 0.25 ug Anti-Human ICOS/CD278 Rabbit Recombinant Antibody (98214-1-RR, Clone: 241770G11) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). 1x10^6 untreated human PBMCs were surface stained with 0.25 ug Anti-Human ICOS/CD278 Rabbit Recombinant Antibody (98214-1-RR, Clone: 241770G11) (black, dashed). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: PHA treated human PBMCs,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98214-1-RR cible ICOS/CD278 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: inducible T-cell co-stimulator
• Masse moléculaire calculée: 199 aa, 23 kDa
• Numéro d’acquisition GenBank: BC028210
• Symbole du gène: ICOS
• Identification du gène (NCBI): 29851
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

Inducible T cell co-stimulator (ICOS) is related to the CD28 superfamily and is highly expressed on activated T cells as well as regulatory T cells and is crucial for the survival and function of T cells, Th2 cell differentiation, and lung inflammatory responses. Binding ICOS to ICOS-ligand (ICOS-L) activates a cascade of intracellular signaling molecules that prevent apoptosis and lead to the production of cytokines such as IL-4 and IL-13.

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