Anticorps Recombinant de lapin anti-ICOS/CD278

ICOS/CD278 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

APC Fluorescent Dye

CloneNo.

241770G11

N° de cat : APC-FcA98214

Synonymes

ICOS, Activation-inducible lymphocyte immunomediatory molecule, AILIM, CD278, CVID1

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Galerie de données de validation

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  FC experiment of human PBMCs using APC-FcA98214

  1x10^6 untreated or PHA-treated human PBMCs were surface stained with 5 ul APC Anti-Human ICOS/CD278 Rabbit RecAb (APC-FcA98214, Clone: 241770G11) and FcZero-rAb™ PE Anti-Human CD3 (UCHT1) Rabbit IgG Recombinant Antibody (PE-FcA65570, Clone: UCHT1). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: PHA treated human PBMCs,

Dilution recommandée

Application	Dilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

APC-FcA98214 cible ICOS/CD278 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: ICOS/CD278 Protéine recombinante Eg1642
• Nom complet: inducible T-cell co-stimulator
• Masse moléculaire calculée: 199 aa, 23 kDa
• Numéro d’acquisition GenBank: BC028210
• Symbole du gène: ICOS
• Identification du gène (NCBI): 29851
• Conjugaison: APC Fluorescent Dye
• Excitation/Emission maxima wavelengths: 650 nm / 660 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

Inducible T cell co-stimulator (ICOS) is related to the CD28 superfamily and is highly expressed on activated T cells as well as regulatory T cells and is crucial for the survival and function of T cells, Th2 cell differentiation, and lung inflammatory responses. Binding ICOS to ICOS-ligand (ICOS-L) activates a cascade of intracellular signaling molecules that prevent apoptosis and lead to the production of cytokines such as IL-4 and IL-13.

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