Anticorps Recombinant de lapin anti-IFI30

IFI30 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

250400A4

N° de cat : 85982-1-PBS

Synonymes

EC:1.8.-.-, Gamma-interferon-inducible lysosomal thiol reductase, Gamma-interferon-inducible protein IP-30, GILT, IFI 30

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Galerie de données de validation

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  WB analysis using 85982-1-RR (same clone as 85982-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85982-1-RR (IFI30 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85982-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 85982-1-RR

  Biolayer interferometry (BLl) kinetic assays of 85982-1-RR against Human IFI30 were performed. The affinity constant is below 1 pM.

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Informations sur le produit

85982-1-PBS cible IFI30 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat

• Réactivité: Humain, rat
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: IFI30 Protéine recombinante Ag2178
• Nom complet: interferon, gamma-inducible protein 30
• Masse moléculaire calculée: 261 aa, 29 kDa
• Poids moléculaire observé: 30-35 kDa
• Numéro d’acquisition GenBank: BC021136
• Symbole du gène: IFI30
• Identification du gène (NCBI): 10437
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

IFI30(interferon, gamma-inducible protein 30) is also named as IP30, GILT, IFI-30, MGC32056, IFI30 and belongs to the GILT family. It can facilitate the processing and presentation to antigen-specific T cells of protein antigens containing disulfide bonds. IFI30 is inducibly up-regulated by IFN-g, as are MHC class II molecules, the associated invariant chain, and HLA-DM, which catalyses peptide loading in MIICs and the 35 kDa species is the IFI30 proform, and the 30-kDa species is the mature form(PMID:10639150). It can exsit as a dimer(PMID:17142755).

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