Anticorps Monoclonal anti-IFIT3

IFIT3 Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2C8B10

N° de cat : 67208-1-PBS

Synonymes

CIG 49, CIG49, GARG 49, IFI 60K, IFI60, IFIT 3, IFIT 4, IFIT3, IFIT4, IRG2, ISG 60, ISG60, RIG G

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Galerie de données de validation

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  WB analysis using 67208-1-Ig (same clone as 67208-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67208-1-Ig (IFIT3 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67208-1-PBS in a different storage buffer formulation.

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  IHC staining of human spleen using 67208-1-Ig (same clone as 67208-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human spleen tissue slide using 67208-1-Ig (IFIT3 antibody) at dilution of 1:300 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67208-1-PBS in a different storage buffer formulation.

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  IHC staining of human spleen using 67208-1-Ig (same clone as 67208-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human spleen tissue slide using 67208-1-Ig (IFIT3 antibody) at dilution of 1:300 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67208-1-PBS in a different storage buffer formulation.

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  IF Staining of HepG2 using 67208-1-Ig (same clone as 67208-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using IFIT3 antibody (67208-1-Ig, Clone: 2C8B10 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67208-1-PBS in a different storage buffer formulation.

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Informations sur le produit

67208-1-PBS cible IFIT3 dans les applications de WB, IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: IFIT3 Protéine recombinante Ag7518
• Nom complet: IFIT3
• Masse moléculaire calculée: 56 kDa
• Poids moléculaire observé: 60 kDa
• Numéro d’acquisition GenBank: BC004977
• Symbole du gène: IFIT3
• Identification du gène (NCBI): 3437
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

IFIT3 (IFN-induced protein with tetratricopeptide repeats 3), also known as IFIT-4, ISG-60 or RIG-G, is a 56 kDa IFN induced protein. IFIT3 has been identified to be associated with strong IFN antiviral activity. Upon RNA virus infection, IFIT3 is significantly induced, ectopic expression or knockdown of IFIT3 could, respectively, enhance or impair IFN regulatory factor 3 (IRF3)-mediated gene expression. IFIT3 thus may serve as an important modulator in innate immunity, revealing a new function of the IFIT family proteins.

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