Anticorps Monoclonal anti-IFITM2-Specific

• Phare
• Validé par KD/KO

IFITM2-Specific Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

3D5F7

N° de cat : 66137-1-PBS

Synonymes

IFITM2, 1 8D, 18D, 3D5F7, DSPA2c

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Galerie de données de validation

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  WB analysis of HepG2 using 66137-1-Ig (same clone as 66137-1-PBS)

  HepG2 cells were subjected to SDS PAGE followed by western blot with 66137-1-Ig (IFITM2-specific antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66137-1-PBS in a different storage buffer formulation.

• 

  WB analysis of recombinant protein using 66137-1-Ig (same clone as 66137-1-PBS)

  IFITM1 (Lane 1), IFITM2 (Lane 2) and IFITM3 (Lane 3) fusion proteins (20ng/lane) were subjected to SDS-PAGE followed by western blot with IFITM2 monoclonal antibody (66137-1-Ig) at dilution of 1:10,000. This data was developed using the same antibody clone with 66137-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HepG2 using 66137-1-Ig (same clone as 66137-1-PBS)

  HepG2 cells were subjected to SDS PAGE followed by western blot with 66137-1-Ig (IFITM2-specific antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66137-1-PBS in a different storage buffer formulation.

• 

  WB analysis of MCF-7 using 66137-1-Ig (same clone as 66137-1-PBS)

  MCF7 cells were subjected to SDS PAGE followed by western blot with 66137-1-Ig (IFITM2-specific antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66137-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66137-1-PBS cible IFITM2-Specific dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: interferon induced transmembrane protein 2 (1-8D)
• Poids moléculaire observé: 15 kDa
• Numéro d’acquisition GenBank: NM_006435
• Symbole du gène: IFITM2
• Identification du gène (NCBI): 10581
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

IFITM2, also named as 1-8D, belongs to the CD225 family. It is an IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus (WNV), and dengue virus (WNV), by inhibiting the early step(s) of replication. IFITM2 induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner. It is overexpressed in colon carcinoma. IFITM2 is a novel pro-apoptotic gene that will provide new insights into the regulated cellular pathways to death.(PMID:19544527) This antibody is specific to IFTIM2.

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