Anticorps Monoclonal anti-IFN Alpha

IFN Alpha Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

4A2A11

N° de cat : 66162-1-PBS

Synonymes

IFL, IFN, IFN ALPHA, IFN alpha 1/13, IFNA@, IFNA1, IFNA13, IFN-alpha, LeIF D

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Galerie de données de validation

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  WB analysis of Transfected HEK-293 using 66162-1-Ig (same clone as 66162-1-PBS)

  WB result of Interferon alpha antibody (66162-1-Ig; 1:300; room temperature for 1.5 hours) with negative control and Interferon alpha overexpressed Transfected HEK-293 cells. This data was developed using the same antibody clone with 66162-1-PBS in a different storage buffer formulation.

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  WB analysis of Recombinant protein using 66162-1-Ig (same clone as 66162-1-PBS)

  Recombinant protein were subjected to SDS PAGE followed by western blot with 66162-1-Ig (Interferon alpha antibody at dilution of 1:40000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66162-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66162-1-PBS cible IFN Alpha dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: IFN Alpha Protéine recombinante Ag12533
• Nom complet: IFNA1
• Masse moléculaire calculée: 189 aa, 22 kDa
• Poids moléculaire observé: 22 kDa
• Numéro d’acquisition GenBank: BC074928
• Symbole du gène: IFN alpha1
• Identification du gène (NCBI): 3439
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

IFNA1 (IF-alpha) is a member of the Type I IFN (1) family best known for their antiviral activity. It is a key cytokine regulating the activity of B cells, T-helper cells (Th cells), cDCs and natural killer cells (NK cells). IFNA1 induces B cell maturation into plasma cells and immunoglobulin production. IFNA1 plays an important role in the pathogenesis of systemic lupus erythematosus (SLE). IFNA1 was the first cytokine to show clinical benefit in the treatment of certain types of cancer, including melanoma, chronic myelogenous leukemia, and renal cancer.

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