Anticorps Polyclonal de lapin anti-IFN-alpha 4/IFNA4

IFN-alpha 4/IFNA4 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 33237-1-PBS

Synonymes

IFNA4, IFN-alpha 4, IFN-alpha-4, IFN-α4 , Interferon alpha 4

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Galerie de données de validation

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  WB analysis using 33237-1-AP (same clone as 33237-1-PBS)

  Human IFN-alpha 4 recombinant protein (Cat No.Eg4962) was subjected to SDS PAGE, followed by western blot with 33237-1-AP (IFN-alpha 4/IFNA4 antibody) at a dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33237-1-PBS in a different storage buffer formulation.

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Informations sur le produit

33237-1-PBS cible IFN-alpha 4/IFNA4 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: IFN-alpha 4/IFNA4 Protéine recombinante Eg4962
• Nom complet: interferon, alpha 4
• Numéro d’acquisition GenBank: BC113642
• Symbole du gène: IFNA4
• Identification du gène (NCBI): 3441
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

IFN-alpha 4 (IFN-α4 or IFNA4) belongs to the type I interferon family, a group of cytokines primarily produced in response to viral infections. As a key player in the innate immune response, IFN-α4 provides the body's first line of defense against pathogens by inducing an antiviral state in neighboring cells. Produced primarily by macrophages, IFN-α4 exerts its antiviral effects by binding to the interferon alpha receptor (IFNAR) on cell surfaces, thereby activating downstream immune signaling pathways . This binding triggers the expression of antiviral proteins, such as a protein kinase and an oligoadenylate synthetase, which inhibit viral RNA replication and enhance natural killer cell cytotoxicity against viruses.

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