Anticorps Polyclonal de lapin anti-IFN Alpha

IFN Alpha Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain et plus (1)

Applications

WB, IHC, IF, ELISA

Conjugaison

Non conjugué

Publications(17)

N° de cat : 18013-1-AP

Synonymes

IFL, IFN, IFN ALPHA, IFN alpha 1/13, IFNA@, IFNA1, IFNA13, IFN-alpha, Interferon alpha 1/13, Interferon alpha D, interferon, alpha 1, Interferon-α1, LeIF D

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Galerie de données de validation

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  WB analysis of Recombinant protein using 18013-1-AP

  Recombinant protein were subjected to SDS PAGE followed by western blot with 18013-1-AP (Interferon alpha antibody at dilution of 1:3000 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: Protéine recombinante

Dilution recommandée

• Western Blot (WB): WB : 1:1000-1:6000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• WB: See 8 publications below
• IHC: See 10 publications below
• IF: See 2 publications below

Informations sur le produit

18013-1-AP cible IFN Alpha dans les applications de WB, IHC, IF, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Réactivité citée: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: IFN Alpha Protéine recombinante Ag12533
• Nom complet: IFNA1
• Masse moléculaire calculée: 189 aa, 22 kDa
• Numéro d’acquisition GenBank: BC074928
• Symbole du gène: IFN alpha1
• Identification du gène (NCBI): 3439
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

IFNA1 (IFN-alpha) is a member of the Type I IFN (1) family best known for their antiviral activity. It is a key cytokine regulating the activity of B cells, T-helper cells (Th cells), cDCs and natural killer cells (NK cells). IFN-alpha induces B cell maturation into plasma cells and immunoglobulin production. IFN-alpha plays an important role in the pathogenesis of systemic lupus erythematosus (SLE). IFN-alpha was the first cytokine to show clinical benefit in the treatment of certain types of cancer, including melanoma, chronic myelogenous leukemia, and renal cancer.

Publications

Species	Application	Title
human	IHC	J Immunother Cancer; Helicobacter pylori infection disturbs the tumor immune microenvironment and is associated with a discrepant prognosis in gastric de novo diffuse large B-cell lymphoma.; Authors - Yuwei Deng
human,mouse	IHC	Cell Death Dis; Enhancing immunotherapy efficacy in colorectal cancer: targeting the FGR-AKT-SP1-DKK1 axis with DCC-2036 (Rebastinib); Authors - Xiguang Chen
human,mouse	WB,IHC	Oncogene; Reciprocal regulation between ferroptosis and STING-type I interferon pathway suppresses head and neck squamous cell carcinoma growth through dendritic cell maturation; Authors - Mingyu Li
human		mBio; Early enterovirus translation deficits extend viral RNA replication and elicit sustained MDA5-directed innate signaling; Authors - Mikhail I Dobrikov
human	IF	Ann Allergy Asthma Immunol; Lower viral loads in subjects with rhinovirus-challenged allergy despite reduced innate immunity.; Authors - Xin Feng
mouse	IHC	Immunol Lett; Acute Effects of TLR3 agonist Poly(I:C) on Bone Marrow Hematopoietic Progenitor Cells in Mice; Authors - Xin Shu

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