Anticorps Recombinant de lapin anti-IFNAR1

IFNAR1 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

230549B1

N° de cat : 98067-1-RR

Synonymes

IFN alpha REC, Cytokine receptor class-II member 1, CRF2-1, CRF2 1, AVP

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Galerie de données de validation

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  FC experiment of U-937 using 98067-1-RR

  1x10^6 U-937 cells were surface stained with 0.25 ug Anti-Human IFNAR1 Rabbit Recombinant Antibody (98067-1-RR, Clone:230549B1) and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)(red), or 0.25 ug Isotype Control (blue). Cells were not fixed.

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  Affinity and Kinetic Characterization of 98067-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98067-1-RR against Human IFNAR1 were performed. The affinity constant is 1.15 nM.

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Applications testées

• Résultats positifs en cytométrie: cellules U-937,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98067-1-RR cible IFNAR1 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: interferon (alpha, beta and omega) receptor 1
• Masse moléculaire calculée: 557 aa, 64 kDa
• Numéro d’acquisition GenBank: BC021825
• Symbole du gène: IFNAR1
• Identification du gène (NCBI): 3454
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

Interferon alpha and beta receptor subunit 1 (IFNAR1) is a type I membrane protein that associates with IFNAR2 to form the receptor for type I interferons, including interferons-alpha, -beta, and -lambda. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2, and then increase transcription of the IFN-induced genes whose products exert antiviral, immunomodulatory, and antiproliferative effects.

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