Anticorps Recombinant de lapin anti-IFNAR1

IFNAR1 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

PE Fluorescent Dye

CloneNo.

230549B1

N° de cat : PE-FcA98067

Synonymes

230549B1, AVP, CRF2 1, CRF2-1, Cytokine receptor class-II member 1

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Galerie de données de validation

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  FC experiment of U-937 using PE-FcA98067

  1x10^6 U-937 cells were surface stained with 5 ul PE Anti-Human IFNAR1 Rabbit RecAb (PE-FcA98067, Clone: 230549B1) (red) or PE Rabbit IgG Isotype Control RecAb (PE-FcA98136, Clone: 240953C9) (blue). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: cellules U-937,

Dilution recommandée

Application	Dilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

PE-FcA98067 cible IFNAR1 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: IFNAR1 Protéine recombinante Eg0156
• Nom complet: interferon (alpha, beta and omega) receptor 1
• Masse moléculaire calculée: 557 aa, 64 kDa
• Numéro d’acquisition GenBank: BC021825
• Symbole du gène: IFNAR1
• Identification du gène (NCBI): 3454
• Conjugaison: PE Fluorescent Dye
• Excitation/Emission maxima wavelengths: 496 nm, 565 nm / 578 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

Interferon alpha and beta receptor subunit 1 (IFNAR1) is a type I membrane protein that associates with IFNAR2 to form the receptor for type I interferons, including interferons-alpha, -beta, and -lambda. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2, and then increase transcription of the IFN-induced genes whose products exert antiviral, immunomodulatory, and antiproliferative effects.

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