Anticorps Polyclonal de lapin anti-IGFALS

IGFALS Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 24545-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of human plasma using 24545-1-AP (same clone as 24545-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 24545-1-AP (IGFALS antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24545-1-PBS in a different storage buffer formulation.

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Informations sur le produit

24545-1-PBS cible IGFALS dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: IGFALS Protéine recombinante Ag21696
• Nom complet: insulin-like growth factor binding protein, acid labile subunit
• Masse moléculaire calculée: 605 aa, 66 kDa
• Poids moléculaire observé: 85 kDa
• Numéro d’acquisition GenBank: BC025681
• Symbole du gène: IGFALS
• Identification du gène (NCBI): 3483
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

THE ACID-LABILE SUBUNIT (ALS), a liver-derived, GH-dependent, 85-kD glycoprotein, is a key component of the 150-kD IGF circulating ternary complex(PMID: 17726072). The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty.

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