Anticorps Polyclonal de lapin anti-IGFBP4

• Phare
• Validé par KD/KO

IGFBP4 Polyclonal Antibody for WB, IHC, IF/ICC, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat

Applications

WB, IHC, IF/ICC, ELISA

Conjugaison

Non conjugué

N° de cat : 18500-1-PBS

Synonymes

BP 4, BP4, Deb2, HT29 IGFBP, IBP 4

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Galerie de données de validation

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  WB analysis of C6 using 18500-1-AP (same clone as 18500-1-PBS)

  C6 cells were subjected to SDS PAGE followed by western blot with 18500-1-AP (IGFBP4 Antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18500-1-PBS in a different storage buffer formulation.

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  WB analysis of C6 using 18500-1-AP (same clone as 18500-1-PBS)

  C6 cells were subjected to SDS PAGE followed by western blot with 18500-1-AP (IGFBP4 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18500-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 18500-1-AP (same clone as 18500-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 18500-1-AP (IGFBP4 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 18500-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 18500-1-AP (same clone as 18500-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 18500-1-AP (IGFBP4 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 18500-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon using 18500-1-AP (same clone as 18500-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 18500-1-AP (IGFBP4 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 18500-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon using 18500-1-AP (same clone as 18500-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 18500-1-AP (IGFBP4 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 18500-1-PBS in a different storage buffer formulation.

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  IF Staining of C6 using 18500-1-AP (same clone as 18500-1-PBS)

  Immunofluorescent analysis of C6 cells using 18500-1-AP (IGFBP4 antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 18500-1-PBS in a different storage buffer formulation.

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Informations sur le produit

18500-1-PBS cible IGFBP4 dans les applications de WB, IHC, IF/ICC, ELISA et montre une réactivité avec des échantillons Humain, rat

• Réactivité: Humain, rat
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: IGFBP4 Protéine recombinante Ag13347
• Nom complet: insulin-like growth factor binding protein 4
• Masse moléculaire calculée: 28 kDa
• Poids moléculaire observé: 28-40 kDa
• Numéro d’acquisition GenBank: BC016041
• Symbole du gène: IGFBP4
• Identification du gène (NCBI): 3487
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

IGFBP4, also named as IBP4, is a 258 amino acid protein, which contains one IGFBP N-terminal domain and one thyroglobulin type-1 domain. IGFBP4 is the smallest member of the insulin-like growth factor binding protein family (IGFBP). It is a hepatic protein that plays a role in modulating the activity and bioavailability of IGF-I. The expression of IGFBP4 was found to increase under conditions of hypoxia. IGFBP4 is highly expressed in adipocytes and osteoblasts and is inhibitory of IGFs in vitro. (PMID: 28938423, PMID: 34646401). IGFBP4 is a secreted protein and calculated molecular weight is 28 kDa.

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