Anticorps Polyclonal de lapin anti-IGFBP4

IGFBP4 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 30952-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 30952-1-AP (same clone as 30952-1-PBS)

  MDA-MB-231 cells lysates were subjected to SDS PAGE followed by western blot with 30952-1-AP (IGFBP4 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30952-1-PBS in a different storage buffer formulation.

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Informations sur le produit

30952-1-PBS cible IGFBP4 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: insulin-like growth factor binding protein 4
• Masse moléculaire calculée: 28 kDa
• Poids moléculaire observé: 28-40 kDa
• Numéro d’acquisition GenBank: NM_001552.3
• Symbole du gène: IGFBP4
• Identification du gène (NCBI): 3487
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

IGFBP4, also named as IBP4, is a 258 amino acid protein, which contains one IGFBP N-terminal domain and one thyroglobulin type-1 domain. IGFBP4 is the smallest member of the insulin-like growth factor binding protein family (IGFBP). It is a hepatic protein that plays a role in modulating the activity and bioavailability of IGF-I. The expression of IGFBP4 was found to increase under conditions of hypoxia. IGFBP4 is highly expressed in adipocytes and osteoblasts and is inhibitory of IGFs in vitro. (PMID: 28938423, PMID: 34646401).

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