Anticorps Polyclonal de lapin anti-IKBKAP

IKBKAP Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

N° de cat : 31705-1-AP

Synonymes

IKK complex associated protein, IKAP, FLJ12497, ELP1, Elongator complex protein 1

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Galerie de données de validation

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  WB analysis using 31705-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 31705-1-AP (IKBKAP antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: cellules HeLa, cellules HepG2, cellules U-251

Dilution recommandée

• Western Blot (WB): WB : 1:2000-1:12000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

31705-1-AP cible IKBKAP dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: IKBKAP Protéine recombinante Ag35286
• Nom complet: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
• Masse moléculaire calculée: 150kDa，1332aa
• Poids moléculaire observé: 140-150 kDa
• Numéro d’acquisition GenBank: NM_001318360.1
• Symbole du gène: IKBKAP
• Identification du gène (NCBI): 8518
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

IKBKAP, also known as ELP1. It is expected to be located in the cytoplasm and nucleus, which is ubiquitinated in adrenal and ovary tissue. The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. And it exists in homodimer. The molecular weight of IKBKAP is 150 kDa.

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