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Anticorps Polyclonal de lapin anti-IKBKAP

IKBKAP Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31705-1-PBS

Synonymes

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using IKBKAP Polyclonal antibody (31705-1-AP)

    WB analysis using 31705-1-AP (same clone as 31705-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31705-1-AP (IKBKAP antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31705-1-PBS in a different storage buffer formulation.

Informations sur le produit

31705-1-PBS cible IKBKAP dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène IKBKAP Protéine recombinante Ag35286
Nom complet inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
Masse moléculaire calculée150kDa，1332aa
Poids moléculaire observé140-150 kDa
Numéro d’acquisition GenBankNM_001318360.1
Symbole du gène IKBKAP
Identification du gène (NCBI) 8518
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

IKBKAP, also known as ELP1. It is expected to be located in the cytoplasm and nucleus, which is ubiquitinated in adrenal and ovary tissue. The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. And it exists in homodimer. The molecular weight of IKBKAP is 150 kDa.

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