Anticorps Polyclonal de lapin anti-IKZF4

IKZF4 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31094-1-PBS

Synonymes

EOS, IKZF 4, KIAA1782, Zinc finger protein Eos, ZNFN1A4

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Galerie de données de validation

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  WB analysis using 31094-1-AP (same clone as 31094-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31094-1-AP (IKZF4 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31094-1-PBS in a different storage buffer formulation.

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Informations sur le produit

31094-1-PBS cible IKZF4 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: IKZF4 Protéine recombinante Ag34767
• Nom complet: IKAROS family zinc finger 4 (Eos)
• Poids moléculaire observé: 64-70 kDa
• Numéro d’acquisition GenBank: BC160169
• Symbole du gène: IKZF4
• Identification du gène (NCBI): 64375
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

IKZF4 is a member of the Ikaros family transcription factors. The Ikaros family was originally designated to function in hematopoiesis, but it is only recently that studies have begun to show the relevance of this family in T helper cell differentiation. IKZF3 was preferentially expressed in TH17 cells and governs TH17 differentiation by silencing IL-2 expression. By investigating the dynamics of the TH17 regulatory network, IKZF4 was proposed by Yosef et al. as a composite in the negative regulatory module for TH17. (PMID: 24644282)

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