Anticorps Recombinant de lapin anti-IL-1 beta

IL-1 beta Recombinant Antibody for FC (Intra)

Hôte / Isotype

Lapin / IgG

Réactivité testée

rat

Applications

FC (Intra)

Conjugaison

Non conjugué

CloneNo.

241001F11

N° de cat : 98310-2-PBS

Synonymes

Il1 beta, Il1b, IL 1 beta, IL-1 beta,IL 1 beta,IL1beta, IL-1 β

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Galerie de données de validation

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  FC experiment of Transfected HEK-293T using 98310-2-RR (same clone as 98310-2-PBS)

  1x10^6 HEK-293T cells or IL-1 beta transfected HEK-293T cells were intracellularly stained with 0.25 ug Anti-Rat Il1 beta Rabbit RecAb (98310-2-RR, Clone: 241001F11) and Multi-rAb CoraLite ® Plus 647-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR005). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98310-2-PBS in a different storage buffer formulation.

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  FC experiment of Transfected HEK-293T using 98310-2-RR (same clone as 98310-2-PBS)

  1x10^6 HEK-293T cells or IL-1 beta transfected HEK-293T cells were intracellularly stained with 0.25 ug Anti-Rat Il1 beta Rabbit RecAb (98310-2-RR, Clone: 241001F11) and Multi-rAb CoraLite ® Plus 647-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR005) (red), or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98310-2-PBS in a different storage buffer formulation.

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Informations sur le produit

98310-2-PBS cible IL-1 beta dans les applications de FC (Intra) et montre une réactivité avec des échantillons rat

• Réactivité: rat
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: interleukin 1 beta
• Masse moléculaire calculée: 31 kDa
• Numéro d’acquisition GenBank: NM_031512
• Symbole du gène: IL-1 beta
• Identification du gène (NCBI): 24494
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

Interleukin-1, produced mainly by blood monocytes, mediates the panoply of host reactions collectively known as acute phase response. It is identical to endogenous pyrogen. The multiple biologic activities that define IL1 are properties of a 15- to 18-kD protein that is derived from a 30- to 35-kD precursor. Interleukin 1β (IL-1B) is a member of the interleukin 1 cytokine family. It is a pro-inflammatory cytokine against infection, playing an important role in the pathogenesis of cancers. It signals through various adaptor proteins and kinases that lead to activation of numerous downstream targets.

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