Anticorps Recombinant de lapin anti-IL-12RB1/CD212

IL-12RB1/CD212 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

APC Fluorescent Dye

CloneNo.

241661H1

N° de cat : APC-FcA98149

Synonymes

IL12RB1, CD212, IL 12R beta 1, IL 12R subunit beta 1, IL 12RB1

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Galerie de données de validation

• 

  FC experiment of human PBMCs using APC-FcA98149

  1x10^6 anti-CD3/CD28 treated human PBMCs were surface stained with 5 ul APC Anti-Human IL-12RB1/CD212 Rabbit RecAb (APC-FcA98149, Clone: 241661H1) (red) or APC Rabbit IgG Isotype Control RecAb (APC-FcA98136, Clone: 240953C9) (blue). 1x10^6 untreated human PBMCs were surface stained with 5 ul APC Anti-Human IL-12RB1/CD212 Rabbit RecAb (APC-FcA98149, Clone: 241661H1) (black, dashed). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: Anti-CD3/CD28 treated human PBMCs

Dilution recommandée

Application	Dilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

APC-FcA98149 cible IL-12RB1/CD212 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: interleukin 12 receptor, beta 1
• Masse moléculaire calculée: 662 aa, 73 kDa
• Numéro d’acquisition GenBank: BC029121
• Symbole du gène: IL12RB1
• Identification du gène (NCBI): 3594
• Conjugaison: APC Fluorescent Dye
• Excitation/Emission maxima wavelengths: 650 nm / 660 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

Interleukin-12 receptor subunit beta-1 (IL-12RB1), also named as CD212, is a 662 amino acid protein, which contains 5 fibronectin type-III domains and belongs to the type I cytokine receptor family. IL-12RB1 localizes in the membrane and functions as an interleukin receptor which binds IL-12 with low affinity and is involved in IL-12 transduction. Associated with IL-12RB2 it forms a functional, high affinity receptor for IL-12. It can also associate with IL23R to form the interleukin-23 receptor which functions in IL-23 signal transduction probably through activation of the Jak-Stat signaling cascade.

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