Anticorps Recombinant de lapin anti-IL-13RA2

IL-13RA2 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

242742C4

N° de cat : 98407-3-RR

Synonymes

CD213a2, IL-13 receptor subunit alpha-2, IL-13R subunit alpha-2, Il13ra2, IL-13R-alpha-2

---

Galerie de données de validation

• 

  FC experiment of Transfected HEK-293T using 98407-3-RR

  1x10^6 HEK-293T cells (left) and IL-13RA2-transfected HEK-293T cells (right) were surface stained with 0.25 ug Anti-Mouse IL-13RA2 Rabbit RecAb (98407-3-RR, Clone: 242742C4) and APC-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

• 

  FC experiment of Transfected HEK-293T using 98407-3-RR

  1x10^6 HEK-293T cells (left) and IL-13RA2-transfected HEK-293T cells (right) were surface stained with 0.25 ug Anti-Mouse IL-13RA2 Rabbit RecAb (98407-3-RR, Clone: 242742C4) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-2-RR, Clone: 240953A11) (blue), and APC-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

---

Applications testées

• Résultats positifs en cytométrie: Transfected HEK-293T cells,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98407-3-RR cible IL-13RA2 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: IL-13RA2 Protéine recombinante Eg3118
• Nom complet: interleukin 13 receptor, alpha 2
• Masse moléculaire calculée: 44 kDa
• Numéro d’acquisition GenBank: NM_008356.4
• Symbole du gène: Il13ra2
• Identification du gène (NCBI): 16165
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

IL-13RA2, also named as IL-13R and CD213a2, belongs to the type I cytokine receptor family. It binds as a monomer with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4). IL-13RA2 lacks the cytoplasmic domain for signaling, indicating that it acts as a decoy receptor. IL-13RA2 gene polymorphisms have been associated with systemic sclerosis (PMID: 16981293). Overexpression of IL-13RA2 gene has been reported in several types of cancer, including melanoma, lung cancer, and brain tumor, which makes it a potential immunotherapeutic target (PMID: 19895199; 24970476; 24021875).

{{ptg:RelatedPrimaryAntibodies}}