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Anticorps Recombinant de lapin anti-IL-13Ra1/CD213a1

IL-13Ra1/CD213a1 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241834G10

N° de cat : 84525-4-PBS

Synonymes

IL13RA1, 241834G10, Cancer/testis antigen 19, CD213A1, CT19

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using IL-13Ra1/CD213a1 Recombinant antibody (84525-4-RR)

    WB analysis using 84525-4-RR (same clone as 84525-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84525-4-RR (IL-13Ra1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84525-4-PBS in a different storage buffer formulation.

Informations sur le produit

84525-4-PBS cible IL-13Ra1/CD213a1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène IL-13Ra1/CD213a1 Protéine recombinante Eg2320
Nom complet interleukin 13 receptor, alpha 1
Masse moléculaire calculée 49 kDa
Poids moléculaire observé70-75 kDa
Numéro d’acquisition GenBankBC009960
Symbole du gène IL-13Rα1
Identification du gène (NCBI) 3597
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Protein A purfication
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

IL-13 is an immunoregulatory cytokine secreted predominantly by activated T-helper 2 (Th2) cells and performs multiple functions through a complex receptor system comprised of IL-4Rα and two IL-13 binding proteins, IL-13Rα1 and IL-13Rα2 (PMID: 12704343). IL-13Rα1 is a glycosylated transmembrane protein (PMID: 10856136; 9723655). IL-13Rα1 is expressed on a wide range of cells including B cells, monocytes, macrophages, basophils, mast cells, and endothelial cells (PMID: 10856136; 31866859). IL-13 binding to the IL-4Rα/IL-13Rα1 complex leads to activation of JAK1, JAK2, and TYK2 and subsequent phosphorylation of STAT6 and STAT3 (PMID: 31866859).

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