Anticorps Recombinant de lapin anti-IL-13Ra1/CD213a1

IL-13Ra1/CD213a1 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

241834A1

N° de cat : 98216-1-RR

Synonymes

IL13RA1, IL 13R alpha 1, IL 13 receptor subunit alpha 1, CT19, CD213A1

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Galerie de données de validation

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  FC experiment of MCF-7 using 98216-1-RR

  1x10^6 MCF-7 cells (left) or Jurkat cells (right) were surface stained with 0.125 ug Anti-Human IL-13Ra1/CD213a1 Rabbit Recombinant Antibody (98216-1-RR, Clone: 241834A1) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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  Affinity and Kinetic Characterization of 98216-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98216-1-RR against Human IL-13Ra1/CD213a1 were performed. The affinity constant is below 1 pM.

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Applications testées

• Résultats positifs en cytométrie: cellules MCF-7,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98216-1-RR cible IL-13Ra1/CD213a1 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: interleukin 13 receptor, alpha 1
• Masse moléculaire calculée: 49 kDa
• Numéro d’acquisition GenBank: BC009960
• Symbole du gène: IL-13Rα1
• Identification du gène (NCBI): 3597
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

IL-13 is an immunoregulatory cytokine secreted predominantly by activated T-helper 2 (Th2) cells and performs multiple functions through a complex receptor system comprised of IL-4Rα and two IL-13 binding proteins, IL-13Rα1 and IL-13Rα2 (PMID: 12704343). IL-13Rα1 is a glycosylated transmembrane protein (PMID: 10856136; 9723655). IL-13Rα1 is expressed on a wide range of cells including B cells, monocytes, macrophages, basophils, mast cells, and endothelial cells (PMID: 10856136; 31866859). IL-13 binding to the IL-4Rα/IL-13Rα1 complex leads to activation of JAK1, JAK2, and TYK2 and subsequent phosphorylation of STAT6 and STAT3 (PMID: 31866859).

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