Anticorps Recombinant de lapin anti-IL-17C

IL-17C Recombinant Antibody for FC (Intra)

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC (Intra)

Conjugaison

Non conjugué

CloneNo.

250601C2

N° de cat : 98556-1-PBS

Synonymes

Cytokine CX2, Il17c, Interleukin-17C

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Galerie de données de validation

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  FC experiment of Transfected HEK-293T using 98556-1-RR (same clone as 98556-1-PBS)

  1x10^6 HEK-293T cells or IL-17C transfected HEK-293T cells were intracellularly stained with 0.25 ug Anti-Mouse IL-17C Rabbit RecAb (98556-1-RR, Clone: 250601C2) and APC-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were fixed with Intracellular Flow Cytometry Fixation & Permeabilization Buffer Kit (PF00019). This data was developed using the same antibody clone with 98556-1-PBS in a different storage buffer formulation.

• 

  FC experiment of Transfected HEK-293T using 98556-1-RR (same clone as 98556-1-PBS)

  1x10^6 HEK-293T cells or IL-17C transfected HEK-293T cells were intracellularly stained with 0.25 ug Anti-Mouse IL-17C Rabbit RecAb (98556-1-RR, Clone: 250601C2) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and APC-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were fixed with Intracellular Flow Cytometry Fixation & Permeabilization Buffer Kit (PF00019). This data was developed using the same antibody clone with 98556-1-PBS in a different storage buffer formulation.

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Informations sur le produit

98556-1-PBS cible IL-17C dans les applications de FC (Intra) et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: IL-17C Protéine recombinante Eg2840
• Nom complet: interleukin 17C
• Masse moléculaire calculée: 22 kDa
• Numéro d’acquisition GenBank: NM_145834.3
• Symbole du gène: Il17c
• Identification du gène (NCBI): 234836
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

IL-17C is a member of the IL-17 cytokine family, was cloned from a human fetal kidney library in 2000 (PMID: 10639155). The IL-17 family comprises at least 6 proinflammatory cytokines that share a conserved cystine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins that induce local cytokine production and recruit granulocytes to sites of inflammation (PMID: 15485625; 11574464). IL-17C is selectively induced in epithelia by bacterial challenge and inflammatory stimuli (PMID: 21993848). IL-17RE is a receptor specific to IL-17C and has an essential role in host mucosal defense against infection (PMID: 21993849).

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