Anticorps Recombinant de lapin anti-IL-17C

IL-17C Recombinant Antibody for FC (Intra)

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC (Intra)

Conjugaison

Non conjugué

CloneNo.

250601C2

N° de cat : 98556-1-RR

Synonymes

Cytokine CX2, Il17c, Interleukin-17C

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Galerie de données de validation

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  FC experiment of Transfected HEK-293T using 98556-1-RR

  1x10^6 HEK-293T cells or IL-17C transfected HEK-293T cells were intracellularly stained with 0.25 ug Anti-Mouse IL-17C Rabbit RecAb (98556-1-RR, Clone: 250601C2) and APC-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were fixed with Intracellular Flow Cytometry Fixation & Permeabilization Buffer Kit (PF00019).

• 

  FC experiment of Transfected HEK-293T using 98556-1-RR

  1x10^6 HEK-293T cells or IL-17C transfected HEK-293T cells were intracellularly stained with 0.25 ug Anti-Mouse IL-17C Rabbit RecAb (98556-1-RR, Clone: 250601C2) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and APC-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were fixed with Intracellular Flow Cytometry Fixation & Permeabilization Buffer Kit (PF00019).

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Applications testées

• Résultats positifs en FC (Intra): Transfected HEK-293T cells,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98556-1-RR cible IL-17C dans les applications de FC (Intra) et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: IL-17C Protéine recombinante Eg2840
• Nom complet: interleukin 17C
• Masse moléculaire calculée: 22 kDa
• Numéro d’acquisition GenBank: NM_145834.3
• Symbole du gène: Il17c
• Identification du gène (NCBI): 234836
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

IL-17C is a member of the IL-17 cytokine family, was cloned from a human fetal kidney library in 2000 (PMID: 10639155). The IL-17 family comprises at least 6 proinflammatory cytokines that share a conserved cystine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins that induce local cytokine production and recruit granulocytes to sites of inflammation (PMID: 15485625; 11574464). IL-17C is selectively induced in epithelia by bacterial challenge and inflammatory stimuli (PMID: 21993848). IL-17RE is a receptor specific to IL-17C and has an essential role in host mucosal defense against infection (PMID: 21993849).

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