Anticorps Recombinant de lapin anti-IL-17RA

IL-17RA Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

250349C6

N° de cat : 98532-2-RR

Synonymes

CD217, IL-17 receptor A, Il17r, Il17ra, Interleukin-17 receptor A

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Galerie de données de validation

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  FC experiment of mouse bone marrow cells using 98532-2-RR

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse IL-17RA Rabbit RecAb (98532-2-RR, Clone: 250349C6) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with APC Anti-Mouse Ly-6G/Ly-6C (Gr-1). Cells were not fixed.

• 

  FC experiment of mouse bone marrow cells using 98532-2-RR

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse IL-17RA Rabbit RecAb (98532-2-RR, Clone: 250349C6) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: cellules médullaires de souris,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98532-2-RR cible IL-17RA dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: IL-17RA Protéine recombinante Eg2584
• Nom complet: interleukin 17 receptor A
• Masse moléculaire calculée: 98kDa
• Numéro d’acquisition GenBank: NM_008359.2
• Symbole du gène: Il17ra
• Identification du gène (NCBI): 16172
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

IL-17 is a proinflammatory cytokine. IL-17 can signal as homodimers or heterodimers through a heterodimeric receptor formed by IL-17 receptor A (IL-17RA) and IL-17 receptor C (IL-17RC) subunits. IL-17RA is ubiquitously expressed in both the epithelial and hematopoietic cell compartments. IL-17/IL-17RA signaling plays an important physiological role in regulating the mucosal host defense against invading microorganisms, but it can also play pathogenic roles in several inflammatory or autoimmune conditions; furthermore, it has been described as pro-tumorigenic in several cancer types.

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