Anticorps Recombinant de lapin anti-IL-17RA

IL-17RA Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

APC Fluorescent Dye

CloneNo.

241891G7

N° de cat : APC-FcA98271

Synonymes

CD217, IL17RA, 241891G7, CANDF5, CDw217

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Galerie de données de validation

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  FC experiment of human peripheral blood leukocyte using APC-FcA98271

  1x10^6 human peripheral blood leukocytes were surface stained with FcZero-rAb™ PE Anti-Human CD16, and 5 ul APC Anti-Human IL-17RA Rabbit RecAb (APC-FcA98271, Clone: 241891G7) or APC Rabbit IgG Isotype Control RecAb (APC-FcA98136, Clone: 240953C9). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: human peripheral blood leukocytes

Dilution recommandée

Application	Dilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

APC-FcA98271 cible IL-17RA dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: IL-17RA Protéine recombinante Eg2317
• Nom complet: interleukin 17 receptor A
• Masse moléculaire calculée: 866 aa, 96 kDa
• Numéro d’acquisition GenBank: BC011624
• Symbole du gène: IL17RA
• Identification du gène (NCBI): 23765
• Conjugaison: APC Fluorescent Dye
• Excitation/Emission maxima wavelengths: 650 nm / 660 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

IL-17 is a proinflammatory cytokine. IL-17 can signal as homodimers or heterodimers through a heterodimeric receptor formed by IL-17 receptor A (IL-17RA) and IL-17 receptor C (IL-17RC) subunits. IL-17RA is ubiquitously expressed in both the epithelial and hematopoietic cell compartments. IL-17/IL-17RA signaling plays an important physiological role in regulating the mucosal host defense against invading microorganisms, but it can also play pathogenic roles in several inflammatory or autoimmune conditions; furthermore, it has been described as pro-tumorigenic in several cancer types.

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