Anticorps Recombinant de lapin anti-IL-17RA

IL-17RA Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

241891G7

N° de cat : 98271-1-RR

Synonymes

CD217, IL17RA, 241891G7, CANDF5, CDw217

---

Galerie de données de validation

• 

  FC experiment of human peripheral blood leukocytes using 98271-1-RR

  1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human IL-17RA/CD217 Rabbit Recombinant Antibody (98271-1-RR, Clone: 241891G7) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Human CD16 (3G8). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

• 

  FC experiment of human peripheral blood leukocytes using 98271-1-RR

  1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human IL-17RA/CD217 Rabbit Recombinant Antibody (98271-1-RR, Clone: 241891G7) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

• 

  Affinity and Kinetic Characterization of 98271-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98271-1-RR against Human IL-17RA/CD217 were performed. The affinity constant is 0.115 nM.

---

Applications testées

• Résultats positifs en cytométrie: human peripheral blood leukocytes

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98271-1-RR cible IL-17RA dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: IL-17RA Protéine recombinante Eg2317
• Nom complet: interleukin 17 receptor A
• Masse moléculaire calculée: 866 aa, 96 kDa
• Numéro d’acquisition GenBank: BC011624
• Symbole du gène: IL17RA
• Identification du gène (NCBI): 23765
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

IL-17 is a proinflammatory cytokine. IL-17 can signal as homodimers or heterodimers through a heterodimeric receptor formed by IL-17 receptor A (IL-17RA) and IL-17 receptor C (IL-17RC) subunits. IL-17RA is ubiquitously expressed in both the epithelial and hematopoietic cell compartments. IL-17/IL-17RA signaling plays an important physiological role in regulating the mucosal host defense against invading microorganisms, but it can also play pathogenic roles in several inflammatory or autoimmune conditions; furthermore, it has been described as pro-tumorigenic in several cancer types.

{{ptg:RelatedPrimaryAntibodies}}