Anticorps Recombinant de lapin anti-IL-17RB

IL-17RB Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242967E11

N° de cat : 85961-1-PBS

Synonymes

Evi27, IL-17 receptor B, IL-17 receptor homolog 1, IL-17B receptor, Il17br

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Galerie de données de validation

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  WB analysis using 85961-1-RR (same clone as 85961-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85961-1-RR (IL-17RB antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85961-1-PBS in a different storage buffer formulation.

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  WB analysis of Transfected HEK-293T using 85961-1-RR (same clone as 85961-1-PBS)

  Untransfected HEK-293T cells or mouse IL-17RB-transfected HEK-293T cells were subjected to SDS PAGE followed by western blot with 85961-1-RR (IL-17RB antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85961-1-PBS in a different storage buffer formulation.

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Informations sur le produit

85961-1-PBS cible IL-17RB dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons rat, souris

• Réactivité: rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: IL-17RB Protéine recombinante Eg2798
• Nom complet: interleukin 17 receptor B
• Masse moléculaire calculée: 56 kDa
• Poids moléculaire observé: 67 kDa
• Numéro d’acquisition GenBank: NM_019583.3
• Symbole du gène: Il17rb
• Identification du gène (NCBI): 50905
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

IL-17RB is a transmembrane protein that belongs to the IL-17 receptor family. IL-17RB has a SEFIR cytoplasmic domain implicated in homotypic dimerization and recruitment of signaling proteins (shared with IL-17RA) and a TRAF6-binding domain (not found in IL-17RA). IL-17RB is expressed in various endocrine tissues and epithelial cells in different organs such as kidney, liver, and mucosal tissues. The IL-17B/IL-17RB pathway is considered as a signaling cascade that promotes cancer cell survival, proliferation and migration. The pro-tumor functions associated with the IL 17B/IL-17RB pathway are diverse and complex because they involve mechanisms that act directly on tumor cells, and also indirect mechanisms that lead to tumor microenvironment remodeling.

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