Anticorps Recombinant de lapin anti-IL-1R2

IL-1R2 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

242602C1

N° de cat : 98347-1-PBS

Synonymes

IL-1R-2, Il1r2, IL-1 type II receptor, CD121b, CD121 antigen-like family member B

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Galerie de données de validation

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  FC experiment of mouse bone marrow cells using 98347-1-RR (same clone as 98347-1-PBS)

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse IL-1R2 Rabbit RecAb (98347-1-RR, Clone: 242602C1) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-conjugated Goat Anti-Rabbit IgG. Cells were not fixed. This data was developed using the same antibody clone with 98347-1-PBS in a different storage buffer formulation.

• 

  FC experiment of mouse bone marrow cells using 98347-1-RR (same clone as 98347-1-PBS)

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse IL-1R2 Rabbit RecAb (98347-1-RR, Clone:242602C1) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-conjugated Goat Anti-Rabbit IgG. Cells were not fixed. This data was developed using the same antibody clone with 98347-1-PBS in a different storage buffer formulation.

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Informations sur le produit

98347-1-PBS cible IL-1R2 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: interleukin 1 receptor, type II
• Masse moléculaire calculée: 46 kDa
• Numéro d’acquisition GenBank: NM_010555.4
• Symbole du gène: Il1r2
• Identification du gène (NCBI): 16178
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

Interleukin-1 receptor type 2 (IL1R2, also known as CD121b) is a cytokine receptor that belongs to the interleukin 1 receptor family. It exists in both a membrane bound and soluble form. IL1R2 binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. IL1R2 serves as a negative regulator of IL-1 signaling, thereby suppressing inflammatory response.

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