Anticorps Recombinant de lapin anti-IL-1RAP

IL-1RAP Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

240756A12

N° de cat : 98073-1-RR

Synonymes

IL1RAP, 240756A12, C3orf13, EC:3.2.2.6, IL 1R 3

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Galerie de données de validation

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  FC experiment of human PBMCs using 98073-1-RR

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human IL-1RAP Rabbit RecAb (98073-1-RR, Clone:240756A12) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human CD14 Rabbit Recombinant Antibody (CL647-98040, Clone: 230332D7). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

• 

  FC experiment of human PBMCs using 98073-1-RR

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human IL-1RAP Rabbit RecAb (98073-1-RR, Clone:240756A12) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

• 

  Affinity and Kinetic Characterization of 98073-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98073-1-RR against Human IL-1RAP were performed. The affinity constant is 0.572 nM.

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Applications testées

• Résultats positifs en cytométrie: CMSP humaines

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98073-1-RR cible IL-1RAP dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: IL-1RAP Protéine recombinante Eg0827
• Nom complet: interleukin 1 receptor accessory protein
• Masse moléculaire calculée: 65 kDa
• Numéro d’acquisition GenBank: NM_002182.4
• Symbole du gène: IL1RAP
• Identification du gène (NCBI): 3556
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

IL-1RAP (Interleukin-1 receptor accessory protein), also known as IL-1RAcP, IL-1R-3, or IL-1R3, is a member of the interleukin-1 receptor family. IL-1RAP is composed of an extracellular region containing three Ig-like C2 type domains, a transmembrane region, and a cytoplasmic region with a TIR (Toll-IL-1-receptor) domain. IL-1RAP functions as a co-receptor for IL-1, IL-33, IL-36. It plays an essential role in the signaling of the IL-1 family cytokines such as IL-1, IL-33, and IL-36, as well as tyrosine kinases FLT3 and c-Kit. IL-1RAP can also exist in a soluble form.

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