Anticorps Recombinant de lapin anti-IL-1RAP

IL-1RAP Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

CoraLite®594 Fluorescent Dye

CloneNo.

240756A12

N° de cat : CL594-98073

Synonymes

IL1RAP, 240756A12, C3orf13, EC:3.2.2.6, IL 1R 3

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Galerie de données de validation

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  FC experiment of human PBMCs using CL594-98073

  1x10^6 FC receptor blocked human PBMCs were surface stained with CoraLite® Plus 488 Anti-Human CD14, and 5 ul CoraLite®594 Anti-Human IL-1RAP Rabbit RecAb (CL594-98073, Clone:240756A12) or Rabbit Recombinant Antibody (CL488-98040, Clone: 230332D7). Cells were not fixed.

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  FC experiment of human PBMCs using CL594-98073

  1x10^6 FC receptor blocked human PBMCs were surface stained with 5 ul CoraLite®594 Anti-Human IL-1RAP Rabbit RecAb (CL594-98073, Clone: 240756A12) (red) or Rabbit Recombinant Antibody (CL488-98040, Clone: 230332D7) (blue). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: CMSP humaines

Dilution recommandée

Application	Dilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL594-98073 cible IL-1RAP dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: IL-1RAP Protéine recombinante Eg0827
• Nom complet: interleukin 1 receptor accessory protein
• Masse moléculaire calculée: 65 kDa
• Numéro d’acquisition GenBank: NM_002182.4
• Symbole du gène: IL1RAP
• Identification du gène (NCBI): 3556
• Conjugaison: CoraLite®594 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 588 nm / 604 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

IL-1RAP (Interleukin-1 receptor accessory protein), also known as IL-1RAcP, IL-1R-3, or IL-1R3, is a member of the interleukin-1 receptor family. IL-1RAP is composed of an extracellular region containing three Ig-like C2 type domains, a transmembrane region, and a cytoplasmic region with a TIR (Toll-IL-1-receptor) domain. IL-1RAP functions as a co-receptor for IL-1, IL-33, IL-36. It plays an essential role in the signaling of the IL-1 family cytokines such as IL-1, IL-33, and IL-36, as well as tyrosine kinases FLT3 and c-Kit. IL-1RAP can also exist in a soluble form.

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