Anticorps Polyclonal de lapin anti-IL-21

IL-21 Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 17625-1-PBS

Synonymes

---

Galerie de données de validation

• 

  IHC staining of mouse skin using 17625-1-AP (same clone as 17625-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse skin tissue slide using 17625-1-AP (IL-21 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17625-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse skin using 17625-1-AP (same clone as 17625-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse skin tissue slide using 17625-1-AP (IL-21 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17625-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

17625-1-PBS cible IL-21 dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: IL-21 Protéine recombinante Ag11838
• Nom complet: interleukin 21
• Masse moléculaire calculée: 162 aa, 19 kDa
• Numéro d’acquisition GenBank: BC066258
• Symbole du gène: IL-21
• Identification du gène (NCBI): 59067
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Interleukin 21 (IL-21) is a cytokine produced predominantly by cluster of differentiation 4 (CD4+) T-cells and natural killer T-cells. IL-21 is preliminarily expressed in activated cluster of differentiation 4 (CD4+) T-cells and natural killer (NK) T-cells. IL-21 receptor (IL-21R) is a class I cytokine receptor, which requires dimerization with the indispensable common gamma chain (γc) subunit to bind IL-21. IL-21 plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. IL-21 mediates apoptosis in B-CLL cells through up-regulation of the BIM (BH3 family member) and enhances both direct and antibody-dependent cellular cytotoxicity in these cells.

{{ptg:RelatedPrimaryAntibodies}}