Anticorps Monoclonal anti-IL-21R

IL-21R Monoclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Mouse / IgG2b

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1D1C2

N° de cat : 66319-1-PBS

Synonymes

IL21R, IL-21 receptor, IL 21R, IL 21 receptor, CD360

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Galerie de données de validation

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  WB analysis using 66319-1-Ig (same clone as 66319-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 66319-1-Ig (IL-21R antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66319-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 66319-1-Ig (same clone as 66319-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 66319-1-Ig (IL-21R antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66319-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 66319-1-Ig (same clone as 66319-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 66319-1-Ig (IL-21R antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66319-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human tonsillitis using 66319-1-Ig (same clone as 66319-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 66319-1-Ig (IL21R antibody) at dilution of 1:100 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66319-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human tonsillitis using 66319-1-Ig (same clone as 66319-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 66319-1-Ig (IL21R antibody) at dilution of 1:100 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66319-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66319-1-PBS cible IL-21R dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2b
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: IL-21R Protéine recombinante Ag21295
• Nom complet: interleukin 21 receptor
• Masse moléculaire calculée: 59 kDa
• Poids moléculaire observé: 55-65 kDa
• Numéro d’acquisition GenBank: BC004348
• Symbole du gène: IL-21R
• Identification du gène (NCBI): 50615
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

IL21R, a receptor for interleukin-21, belongs to the type I cytokine receptor family. IL21R has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3.

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