Anticorps Polyclonal de lapin anti-IL-23R

IL-23R Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 27163-1-PBS

Synonymes

IL23R, Interleukin-23 receptor, interleukin 23 receptor, IL-23 receptor, IL 23R

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Galerie de données de validation

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  WB analysis using 27163-1-AP (same clone as 27163-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 27163-1-AP (IL23R antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27163-1-PBS in a different storage buffer formulation.

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  WB analysis using 27163-1-AP (same clone as 27163-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 27163-1-AP (IL23R antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27163-1-PBS in a different storage buffer formulation.

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  IHC staining of human tonsillitis using 27163-1-AP (same clone as 27163-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 27163-1-AP (IL23R antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27163-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human tonsillitis using 27163-1-AP (same clone as 27163-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 27163-1-AP (IL23R antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27163-1-PBS in a different storage buffer formulation.

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Informations sur le produit

27163-1-PBS cible IL-23R dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: IL-23R Protéine recombinante Ag25939
• Nom complet: interleukin 23 receptor
• Masse moléculaire calculée: 72 kDa
• Poids moléculaire observé: 65-75 kDa
• Numéro d’acquisition GenBank: NM_144701
• Symbole du gène: IL-23R
• Identification du gène (NCBI): 149233
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Interleukin-23 receptor (IL-23R) is a type I cytokine receptor that plays a critical role in immune responses and inflammation. It forms a receptor complex with IL-12Rβ1 and is activated by the cytokine IL-23, which is primarily produced by dendritic cells and activated macrophages (PMID: 39796684). The genetic and epigenetic interactions in the IL-23R/IL-17 axis are associated with elevated expression of IL-17 and inflammatory bowel disease (IBD) pathogenesis (PMID: 21672939).

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